Use of thiolated oligonucleotides as anti-fouling diluents in electrochemical peptide-based sensors

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Use of thiolated oligonucleotides as anti-fouling diluents in electrochemical peptide-based sensors.

We incorporated short thiolated oligonucleotides as passivating diluents in the fabrication of electrochemical peptide-based (E-PB) sensors, with the goal of creating a negatively charged layer capable of resisting non-specific adsorption of matrix contaminants. The E-PB HIV sensors fabricated using these diluents were found to be more specific and selective, while retaining attributes similar ...

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ژورنال

عنوان ژورنال: Chemical Communications

سال: 2014

ISSN: 1359-7345,1364-548X

DOI: 10.1039/c4cc01290a